protein-rna interaction — TargetMol Chemicals

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Search Results for " protein-rna interaction "

Compounds

Cat No.	Product Name	Synonyms	Targets
T22698	TLR3-IN-1	CU CPT 4a	TLR
	TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cell...		TLR
T3653	MX69		Mdm2 , E1/E2/E3 Enzyme , IAP
	MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.		Mdm2 , E1/E2/E3 Enzyme , IAP
T60420	Anticancer agent 73		DNA/RNA Synthesis
	Anticancer agent 73 is an anticancer agent which potently targets transactivation response(TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction. Anticancer agent 73 suppresses the growth and metasta...		DNA/RNA Synthesis
T16703	Quarfloxin	CX-3543	DNA/RNA Synthesis
	Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-...		DNA/RNA Synthesis
T38753	CR-1-31-B
	CR-1-31-B, a synthetic rocaglate, acts as a highly potent inhibitor of eIF4A. By disrupting the interaction between eIF4A and RNA, it effectively obstructs the initiation phase of protein synthesis. Specifically, CR-1-31...
T72920	Azaphilone-9	AZA-9
	Azaphilone-9 (AZA-9) functions as an inhibitor of the HuR-ARE RNA interaction, with an inhibition constant (IC50) of 1.2 μM, by targeting the RNA-binding protein Hu antigen R (HuR). As HuR-RNA interactions play a critica...
T79270	TMV-IN-6
	TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat protein (CP) and disrupting the assembly interaction between...
T62235	CDK-IN-9
	CDK-IN-9 (compound 24) is a potent inhibitor of CDK. CDK-IN-9 is also a molecular gel that induces interaction between CDK12 and DDB1 and is able to act on CDK2/E (IC50: 4 nM). CDK-IN-9 can be used to dephosphorylate ret...
T82758	CDK9-Cyclin T1 PPI-IN-1		CDK
	CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apopt...		CDK
T70247	Clemizole sulfate
	Clemizole sulfate is a drug in clinical development for the treatment of hepatitis C virus (HCV) infection. Clemizole is a novel inhibitor of TRPC5 channels. Clemizole is an H1 antagonist. Clemizole, an antihistamine dru...
T76193	PINT-87aa
	PINT-87aa, an 87-amino acid (aa) peptide encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT), directly interacts with the polymerase associated factor complex (PA...
T83729	Tat-CIRP TFA	Tat-Cold-inducible RNA Binding Protein
	Tat-CIRP, a peptide inhibitor, impedes the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP) by binding to MD-...
T81932	LIN28-IN-1
	LIN28-IN-1 (compound 5) is a selective inhibitor targeting the RNA-binding protein LIN28, specifically binding to its cold shock domain (CSD). This compound robustly interrupts the LIN28-let-7 miRNA interaction with an I...
T78055	MYC-RIBOTAC		c-Myc
	MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. Th...		c-Myc